Lonazep is an anxiolytic and an anti-convulsant medication which belongs to the benzodiazepine group of sedatives. It is used for the management of epilepsy, seizures, managing the coordination and movement disorder akasthesia, panic disorder, anxiety, panic attacks, certain phobic reactions and insomnia. It is also used for psychiatric disorders that underlay anxiety neurosis and against convulsions of different causation as well.

Lonazep is manufactured in India by the Sun Pharmaceutical Company.

Lonazep Tablet Composition and Nature

Lonazep contains Clonazepam which is a benzodiazepine variant. It functions by manipulating the signalling and reception of neurotransmitters in the area of the brain to arrest seizures and also to alleviate anxiety. Clonazepam can cross the blood brain barrier and it is a Central Nervous System(CNS) depressant.

Lonazep Tablet Uses:

Besides being an anti-convulsant, Lonazep is also an anxiolytic and sedative. It begins to have an effect within an hour or so and it can last anywhere between 6 and 12 hours.

• Seizures
• Panic disorder and social phobia with or without agoraphobia
• Movement disorder known as akathisia
• It is used to treat anxiety
• Anxiety and depression comorbidity
• Insomnia
• Post-Traumatic Stress Disorder
• Alcohol withdrawal symptoms or delirium tremens
• Akasthisia, a movement disorder

Lonazep Tablet Side Effects:

There remains a set of incidental or side effects related to the psychotropic drugs especially benzodiazepines.

The drug can cause symptoms like:

• Dizziness, drowsiness and confusion
• It may interfere with memory
• It depresses the Central Nervous System and respiratory paralysis if overdosed upon
• Erectile dysfunction
• Constipation
• Urinary retention
• Dependence
• Withdrawal symptoms

Lonazep Tablet Dosage:

Take Lonazep strictly according to the prescribed dosage as prescribed by your physician. Any deviation from the prescription can prove dangerous. The medication has to be taken at a specific time or times of the day which will be precisely informed to you by your medical practitioner. If ever you miss a dose, it can be remedied by taking the tablet as soon as one remembers it; if the second dosage time is imminent then you can skip the forgotten dose. Do not duplicate the dose in any circumstances.

How Lonazep Tablet works?

Lonazep’s constituent psychotropic clonazepam is a benzodiazepine. It alleviates anxiety Clonazepam’s primary mechanism of action pertains to GABA function in the brain, Gaba is a neurotransmitter which is the receptor for benzodiazepine in the brain. Following a complex neural mechanism the effects of GABA get exacerbated. The anticonvulsant properties too of Lonazep has to do with GABA functionality.

Lonazep Tablet Related Warnings/Precautions:

Lonazep is a CNS depressant and can be lethal if ingested wrongfully. Lonazep and other drugs contain clonazepam or other benzodiazepines and are used as recreational drug owing to their psychotropic effects. Such substance abuse can lead to drug addiction and withdrawal symptoms on cessation which can turn lethal at times.

The patients with a history of suicidal behaviour and /or substance abuse must be prescribed Lonazep with caution. Lonazep must not be taken together with other CNS depressants until expressly prescribed by the psychiatrist. Concomitant use of alcohol or any intoxicant must be refrained from as it may compound the CNS depressant effect of benzodiazepine. Driving while on Lonazep is not advised, likewise working with heavy machinery may pose risks and should be avoided at all costs.

Lonazep Tablet Substitutes:

The following are common substitutes available in the market for Lonazep:

• Rivotril, Abbot
• Clonotril, Torrent Pharmaceuticals Ltd
• Klon 2mg Tabllet, Mayflower India

Lonazep Tablet Interactions:

All the drugs which have an effect on CNS are known to interact with Lonazep and aggravate its sedation causing properties. Substances like alcohol, which also is a CNS depressant interact dangerously with Lonazep. These medications generally include anti-depressants, hypnotics, opioid analgesics, antipsychotics and other other anxiolytics etc. Benzodiazepines interact with certain antibiotics and anti-asthmatic drugs, usage in such cases must be directed specifically by the physician and must be followed ardently by the patient.

Concomitant use of Lonazep with another sedative of benzodiazepine group is sometimes considered as the half-life of different benzodiazepine drugs vary which may be of use to the patient. In this scenario, the possibility of interaction typically increases as the sedative effect of the drugs being used is compounded.

Lonazep Tablet FAQs

1) Is Lonazep safe for pregnant and breastfeeding women?

Ans: In general, Lonazep is not safe for anyone who is pregnant and breastfeeding. There are chances of foetal harm and other complications. Therefore, it must be totally avoided by a pregnant or a breastfeeding woman.

2) Can this medicine be prescribed only by a psychiatrist?

Ans: Although Lonazep has practically total psychiatric domain, it can be prescribed by a general registered medical practitioner as well. If the patient is seeing both a psychiatrist and a physician concurrently, they must surely talk to one another so as to avoid contraindications and unwanted interactions thereby causing harm to the patient.

3) Can you drive or use heavy machinery while you are on this medication?

Ans: It is advisable to avoid driving or using industrial machinery for that matter when a patient is on Lonazep. Driving is also not recommended under any circumstance as the consumption of this medication is known to cause dizziness.

4) Is this medicine addictive or habit forming for a patient who has been prescribed on it?

Ans: Yes, Lonazep, like all other benzodiazepine causes dependence, both physiological and psychological. Therefore, they must be used only for the period prescribed by the medical practitioner and withdrawn safely with the help of his guidance and support.

5) Can Lonazep be used only to treat insomnia?

Ans: Though it is used as a drug to relieve insomnia, but it is considered only a short term cure. And it is rarely used if no other indications other than insomnia are present as there are safer and more suitable hypnotics to treat insomnia than Lonazep.

6) What is meant by non-medical use of Lonazep?

Ans: The drug contains benzodiazepine which has known psychotropic effects i.e. it has a major effect on the patients mood. It is therefore used by some people for recreational purpose, needless to say at huge risk of extreme CNS depression and resultant death.

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